Tirzepatide, marketed as Mounjaro® by Eli Lilly, is the first dual GIP/GLP-1 receptor agonist approved for Type 2 Diabetes (T2D) treatment. Approved by the FDA in May 2022, it improves glycemic control and induces significant weight loss. Clinical trials, including SURPASS-4, showed superior HbA1c and weight reductions compared to other therapies. Tirzepatide also demonstrated lower mortality than insulin glargine during the COVID-19 pandemic, suggesting broader health benefits and potential future applications beyond diabetes.
Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.
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Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.
Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.
Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.