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Bacteriostatic water

Bacteriostatic water

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Substance Overview and History

The Bacteriostatic Water, for Injection (BWFI) serves as an nonpyrogenic solution utilized for diluting or dissolving medications intended for intravenous or subcutaneous injections as well as intramuscular injections.The composition consists of elements including 0.9% benzyl alcohol aimed at preventing impurity formation.Multi dose containers are used for BWFI allowing withdrawals without the risk of contamination.Its pH level falls within a range of 4.5 to 7.0. It typically comes in containers not exceeding 30 mL.The shelf life of BWFI extends to three years. It should be stored at temperatures, below 25°C. When getting ready to administer medications by injecting them into a vein or muscle, A process known as administration, It's important to focus on the specifics of the compounds involved and pay attention when diluting specific medications.  

References:

ScienceDirect. (2023). Bacteriostatic Water for Injection.

Ritchie, G.E., 2006. Pharmaceutical Waters.

Drugs.com. Bacteriostatic Water for Injection. USP

Medicines.org.uk. Bacteriostatic Water for Injection - Summary of Product Characteristics. 

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For more details consult with your doctor or healthcare professional.

FAQ
What is Bacteriostatic Water for Injection (BWFI)?
Bacteriostatic Water for Injection(BWFI) is sterile, non-pyrogenic water containing antimicrobial agents, commonly used to dilute or dissolve drugs for intravenous, intramuscular, or subcutaneous injections.
References:

ScienceDirect. (2023). Bacteriostatic Water for Injection.

How is BWFI different from sterile water?
Unlike sterile water, BWFI contains antimicrobial preservatives, such as benzyl alcohol, to suppress the growth of bacteria, making it suitable for multi-dose use.
References:

Ritchie, G.E., 2006. Pharmaceutical Waters.

What is the purpose of the antimicrobial agent in BWFI ?
The antimicrobial agent, usually benzyl alcohol (0.9% or 1.1%), prevents bacterial growth, allowing the solution to be used multiple times without contamination.
References: