Semax, a heptapeptide analog of the ACTH peptide, shows promise as a treatment for Alzheimer's disease due to its unique neuroprotective and anti-aggregating properties. It works by binding to copper ions (Cu2+) that are involved in the harmful aggregation of amyloid beta protein (Aβ) associated with Alzheimer’s. This binding prevents toxic amyloid fibers from forming and protects neuronal cell membranes from damage. Studies indicate that Semax can effectively reduce Aβ fiber formation in a concentration-dependent manner, suggesting its potential to slow the progression of Alzheimer’s and support brain health.
Sciacca, M.F.M., Naletova, I., Giuffrida, M.L. and Attanasio, F., 2022. Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models. ACS Chemical Neuroscience.
Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.
For detailed information about Ultima-Semax by Ultima Pharmaceuticals, consult with your doctor or healthcare professional.
Sciacca, M.F.M., Naletova, I., Giuffrida, M.L. and Attanasio, F., 2022. Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models. ACS Chemical Neuroscience.
Sciacca, M.F.M., Naletova, I., Giuffrida, M.L. and Attanasio, F., 2022. Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models. ACS Chemical Neuroscience.
Sciacca, M.F.M., Naletova, I., Giuffrida, M.L. and Attanasio, F., 2022. Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models. ACS Chemical Neuroscience.
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