Sildenafil citrate, or Viagra, harnesses the nitric oxide (NO)/cGMP pathway by selectively inhibiting PDE5, an enzyme that naturally breaks down cGMP. Initially researched for angina, the drug’s ability to sustain cGMP and facilitate vasodilation showed promise for erectile dysfunction. Approved in 1998, Viagra quickly became a trusted ED treatment, with users reporting high satisfaction rates. Its dosage flexibility—ranging from 25 mg to 100 mg—allows customization based on individual tolerability. Viagra’s pioneering role has influenced the development of other PDE5 inhibitors, although it continues to be the leading treatment option.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.
Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.
For detailed information about Sildenafil 50 by Hemi Pharma, consult with your doctor or healthcare professional.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.