Delta sleep-inducing peptide (DSIP) was discovered in 1977 in rabbit brain blood during sleep stimulation. Initially linked to slow-wave sleep, its role remains unclear. DSIP regulates hormones, lowering corticotropin and increasing somatotropin and luteinizing hormone. It acts as a stress adaptogen, modulates monoamine oxidase, and supports brain metabolism. In ischemia models, DSIP improves blood flow and reduces neuronal stress. It also enhances Valproate’s anticonvulsant effect, suggesting therapeutic potential in epilepsy and neuroprotection.
Tukhovskaya, E.A., Ismailova, A.M., Shaykhutdinova, E.R., Slashcheva, G.A., Prudchenko, I.A., Mikhaleva, I.I., Khokhlova, O.N., Murashev, A.N., and Ivanov, V.T., 2021. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules.
Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.
For detailed information about DSIP by Livewell Pharmaceuticals, consult with your doctor or healthcare professional.
Tukhovskaya, E.A., Ismailova, A.M., Shaykhutdinova, E.R., Slashcheva, G.A., Prudchenko, I.A., Mikhaleva, I.I., Khokhlova, O.N., Murashev, A.N., and Ivanov, V.T., 2021. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules.
Tukhovskaya, E.A., Ismailova, A.M., Shaykhutdinova, E.R., Slashcheva, G.A., Prudchenko, I.A., Mikhaleva, I.I., Khokhlova, O.N., Murashev, A.N., and Ivanov, V.T., 2021. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules.
Tukhovskaya, E.A., Ismailova, A.M., Shaykhutdinova, E.R., Slashcheva, G.A., Prudchenko, I.A., Mikhaleva, I.I., Khokhlova, O.N., Murashev, A.N., and Ivanov, V.T., 2021. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules.
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