Tirzepatide, sold as Mounjaro®, represents a major advancement in diabetes care. It is the first agent to activate both GIP and GLP-1 receptors, approved by the FDA in 2022. Compared to other drugs, tirzepatide provides stronger reductions in HbA1c and body weight while maintaining a similar safety profile. In the SURPASS-4 trial, it also demonstrated reduced mortality during the COVID-19 pandemic. These results suggest tirzepatide may hold promise not only for T2D but also for related comorbidities like obesity.
Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.
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Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.
Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.
Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.