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T-500, 10
T-500, 10 - Hemi Pharma

T-500, 10 - Hemi Pharma

Brand:
Category:
Substance:
Dosage:
10 mg/ml
Package:
10 ml
Price:
€70.00 - €70.00
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Product Overview
Initially approved as a selective serotonin reuptake inhibitor (SSRI) for premature ejaculation, Dapoxetine has been repurposed as a candidate inhibitor of Zika virus RNA polymerase. It binds specifically to the RdRp “N” pocket, essential for RNA initiation. Surface plasmon resonance confirmed this interaction with a Kd of 49.8 μM. In vitro studies across various cell lines showed potent ZIKV suppression, with low EC50 values and minimal toxicity. These findings, along with its favorable safety and pharmacokinetics, support further antiviral investigation.
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For detailed information about T-500, 10 by Hemi Pharma, consult with your doctor or healthcare professional.

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FAQ
What part of ZIKV does Dapoxetine inhibit?
It targets the RNA-dependent RNA polymerase (RdRp), essential for viral RNA synthesis.
References:
What cell lines showed antiviral response to Dapoxetine?
A549, SNB19, and Vero cells showed reduced ZIKV infection in vitro.
References:
Does Dapoxetine show cytotoxic effects in studies?
No, it demonstrated minimal cytotoxicity during antiviral testing.
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