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Home Swiss Remedies Swiss Remedies
Leucovorin Calcium 50 AMPULES
Leucovorin Calcium 50 AMPULES - Swiss Remedies

Leucovorin Calcium 50 AMPULES - Swiss Remedies

Brand:
Swiss Remedies
Category:
Injectables
Substance:
Folinic Acid
Dosage:
50 mg/ml
Package:
10 ml
Price:
0
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Product Overview

Folinic acid, also known as leucovorin, offers therapeutic benefits for cerebral folate deficiency (CFD) associated with autism spectrum disorder (ASD). It bypasses folate receptor alpha (FRα) dysfunction, often caused by autoantibodies, to restore CSF folate levels. Studies show its ability to improve communication, social interaction, and motor symptoms in ASD patients. Placebo-controlled trials demonstrate leucovorin’s efficacy, with improvements in core ASD symptoms, irritability, and epilepsy in most cases. Side effects like agitation and headache are mild, making it a safe, effective treatment.

References:

Rossignol, D.A., & Frye, R.E. (2021) 'Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis', Journal of Personalized Medicine.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about Leucovorin Calcium 50 AMPULES by Swiss Remedies, consult with your doctor or healthcare professional.

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FAQ
What causes cerebral folate deficiency in ASD?
The most common causes are folate receptor alpha autoantibodies (FRAAs), which block folate transport into the brain, and mitochondrial dysfunction.
References:

Rossignol, D.A., & Frye, R.E. (2021) 'Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis', Journal of Personalized Medicine.

What improvements are seen with Leucovorin in ASD?
Leucovorin has been shown to improve communication, attention, social interaction, motor skills, and reduce irritability and epilepsy in children with ASD.
References:

Rossignol, D.A., & Frye, R.E. (2021) 'Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis', Journal of Personalized Medicine.

Is Leucovorin safe for children with ASD?
Yes, placebo-controlled studies report that Leucovorin is generally well-tolerated. Mild side effects include agitation, headaches, and insomnia in a small percentage of cases.
References:

Rossignol, D.A., & Frye, R.E. (2021) 'Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis', Journal of Personalized Medicine.