IGF DES - Ultima Pharmaceuticals

IGF-1 DES, also known as des-N-(1-3) IGF-1, is a shortened version of IGF-1, lacking the first three N-terminal amino acids. This modification significantly changes its biological behavior, reducing its binding to Insulin-like Growth Factor Binding Proteins (IGFBPs), which typically control IGF-1's bioavailability. With this weaker IGFBP binding, IGF-1 DES achieves higher local concentrations, enhancing its potency. This heightened bioactivity makes IGF-1 DES particularly interesting for research in the nervous system, where it may support neurological recovery and cellular regeneration.

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