IGF-1 DES, or des-N-(1-3) IGF-1, is a truncated form of insulin like growth factor 1, distinguished by the removal of the first three amino acids. This modification enhances its potency allowing for greater biological activity than the full length IGF-1. With lower affinity for insulin like-growth factor binding proteins (IGFBPs), IGF-1 DES achieves higher local concentrations which may aid in neuroprotection and tissue regeneration, making it a candidate for therapeutic applications in neurological recovery and muscle growth.
Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers.
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Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers.
Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers.
Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers.