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Insulin-like Growth Factor-1-DES

Insulin-like Growth Factor-1-DES

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Substance Overview and History

IGF-1 DES, or des-N-(1-3) IGF-1, is a truncated form of insulin like growth factor 1, distinguished by the removal of the first three amino acids. This modification enhances its potency allowing for greater biological activity than the full length IGF-1. With lower affinity for insulin like-growth factor binding proteins (IGFBPs), IGF-1 DES achieves higher local concentrations which may aid in neuroprotection and tissue regeneration, making it a candidate for therapeutic applications in neurological recovery and muscle growth.

References:

Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers. 

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FAQ
What are the potential applications of IGF-1 DES?
IGF-1 DES may be used for neuroprotection, wound healing, and enhancing anabolic processes in the CNS.
References:

Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers. 

What effects does IGF-1 DES have on the body?
It exhibits stronger hypoglycemic and anabolic effects than IGF-1 due to its increased availability in tissues.
References:

Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers. 

Is IGF-1 DES neuroprotective?
Studies suggest that while IGF-1 DES has greater bioactivity, its neuroprotective effects may vary based on dosage and binding interactions.
References:

Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers.