Disagree
Home Ultima Pharmaceuticals Ultima Pharmaceuticals
DES (1-3)
DES (1-3) - Ultima Pharmaceuticals

DES (1-3) - Ultima Pharmaceuticals

Brand:
Category:
Substance:
Package:
1 mg
Price:
$26.00 - $35.00
See options
Product Overview

IGF-1 DES’s unique binding properties to IGFBPs make it an interesting tool for enhancing anabolic responses and potentially aiding recovery in neurological contexts. Animal studies indicate that while IGF-1 DES is highly potent, it may require specific dosages for effective neuroprotection. For example, a lower dose was ineffective in neuroprotection, while a higher dose suggested a protective effect, implying a dose-dependent response. Such findings underscore the need for precise dosing in therapeutic applications to maximize the benefits of IGF-1 DES.

References:

Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers. 

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about DES (1-3) by Ultima Pharmaceuticals, consult with your doctor or healthcare professional.

Products
Show more
Explore More Products
FAQ
What role does IGFBP binding play in IGF-1’s neuroprotection?
IGFBP binding appears essential for IGF-1’s neuroprotection, which is diminished in IGF-1 DES due to its weaker IGFBP affinity.
References:

Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers. 

What did studies on hypoxic-ischemic injury reveal about IGF-1 DES?
In hypoxic-ischemic injury models, IGF-1 DES was less neuroprotective than IGF-1 at equivalent doses, likely due to its IGFBP binding differences.
References:

Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers. 

What dosages of IGF-1 DES were tested in animal models?
Dosages of 2 µg and 150 µg were tested, with only the higher dose showing a neuroprotective trend.
References:

Frontiers in CNS Drug Discovery (2011) Frontiers in CNS Drug Discovery. Bentham Science Publishers.