The Ezetimibe drug has been approved by FDA. Is known to effectively lower blood cholesterol levels by acting on the NPC1L1 protein to prevent cholesterol absorption in the digestive system. Greatly reduces the chances of heart related problems. In a development Ezetemibe has shown promise, in treating cancer by triggering paraptosis in liver cancer cells. Ezetemibe may not just be useful for reducing cholesterol levels but also be used cancer treatment.
Yin, Y., Wu, C., Zhou, Y., Zhang, M., Mai, S., Chen, M., and Wang, H.-Y. (2024) Ezetimibe induces paraptosis through Niemann–Pick C1-like 1 inhibition of mammalian-target-of-rapamycin signaling in hepatocellular carcinoma cells. Genes.
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Yin, Y., Wu, C., Zhou, Y., Zhang, M., Mai, S., Chen, M., and Wang, H.-Y. (2024) Ezetimibe induces paraptosis through Niemann–Pick C1-like 1 inhibition of mammalian-target-of-rapamycin signaling in hepatocellular carcinoma cells. Genes.
Yin, Y., Wu, C., Zhou, Y., Zhang, M., Mai, S., Chen, M., and Wang, H.-Y. (2024) Ezetimibe induces paraptosis through Niemann–Pick C1-like 1 inhibition of mammalian-target-of-rapamycin signaling in hepatocellular carcinoma cells. Genes.
Yin, Y., Wu, C., Zhou, Y., Zhang, M., Mai, S., Chen, M., and Wang, H.-Y. (2024) Ezetimibe induces paraptosis through Niemann–Pick C1-like 1 inhibition of mammalian-target-of-rapamycin signaling in hepatocellular carcinoma cells. Genes.