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Human menopausal gonadotropin

Human menopausal gonadotropin

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Substance Overview and History

Human menopausal gonadotropin with abbreviation "HMG" is a fertility drug made from the urine of postmenopausal women, containing both FSH and LH. It stimulates ovaries during assisted reproductive technology (ART) treatments. Studies comparing HMG to r-hFSH show mixed results, with some indicating similar live birth and pregnancy rates and the choice depends on patient needs and treatment goals.

References:

Bühler, K.F., Fischer, R., Verpillat, P., Allignol, A., Guedes, S., Boutmy, E., Bilger, W., Richter, E., and D’Hooghe, T., 2021. Comparative effectiveness of recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (HMG HP) in assisted reproductive technology (ART) treatments: a non-interventional study in Germany. Reproductive Biology and Endocrinology.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For more details consult with your doctor or healthcare professional.

FAQ
What is human menopausal gonadotropin (HMG)?
It is a fertility drug containing both FSH and LH.
References:

Bühler, K.F., Fischer, R., Verpillat, P., Allignol, A., Guedes, S., Boutmy, E., Bilger, W., Richter, E., and D’Hooghe, T., 2021. Comparative effectiveness of recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (HMG HP) in assisted reproductive technology (ART) treatments: a non-interventional study in Germany. Reproductive Biology and Endocrinology.

How exactly does HMG work?
HMG stimulates egg development in the ovaries.
References:

Bühler, K.F., Fischer, R., Verpillat, P., Allignol, A., Guedes, S., Boutmy, E., Bilger, W., Richter, E., and D’Hooghe, T., 2021. Comparative effectiveness of recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (HMG HP) in assisted reproductive technology (ART) treatments: a non-interventional study in Germany. Reproductive Biology and Endocrinology.

What makes HMG different from r-hFSH?
HMG has both FSH and LH, while r-hFSH only has FSH.
References:

Bühler, K.F., Fischer, R., Verpillat, P., Allignol, A., Guedes, S., Boutmy, E., Bilger, W., Richter, E., and D’Hooghe, T., 2021. Comparative effectiveness of recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (HMG HP) in assisted reproductive technology (ART) treatments: a non-interventional study in Germany. Reproductive Biology and Endocrinology.