Human menopausal gonadotropin (HMG) is a fertility medication with both FSH and LH activity, extracted from postmenopausal women's urine. It stimulates the ovaries in ART cycles. Highly purified HMG (HMG HP) is effective and widely used. Unlike recombinant FSH, which contains only FSH, HMG’s combination of hormones may be beneficial in certain patient groups. Studies show comparable live birth rates between HMG and r-hFSH, though r-hFSH may result in more oocytes. Personal health factors determine the optimal treatment.
Bühler, K.F., Fischer, R., Verpillat, P., Allignol, A., Guedes, S., Boutmy, E., Bilger, W., Richter, E., and D’Hooghe, T., 2021. Comparative effectiveness of recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (HMG HP) in assisted reproductive technology (ART) treatments: a non-interventional study in Germany. Reproductive Biology and Endocrinology.
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Bühler, K.F., Fischer, R., Verpillat, P., Allignol, A., Guedes, S., Boutmy, E., Bilger, W., Richter, E., and D’Hooghe, T., 2021. Comparative effectiveness of recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (HMG HP) in assisted reproductive technology (ART) treatments: a non-interventional study in Germany. Reproductive Biology and Endocrinology.
Bühler, K.F., Fischer, R., Verpillat, P., Allignol, A., Guedes, S., Boutmy, E., Bilger, W., Richter, E., and D’Hooghe, T., 2021. Comparative effectiveness of recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (HMG HP) in assisted reproductive technology (ART) treatments: a non-interventional study in Germany. Reproductive Biology and Endocrinology.
Bühler, K.F., Fischer, R., Verpillat, P., Allignol, A., Guedes, S., Boutmy, E., Bilger, W., Richter, E., and D’Hooghe, T., 2021. Comparative effectiveness of recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (HMG HP) in assisted reproductive technology (ART) treatments: a non-interventional study in Germany. Reproductive Biology and Endocrinology.