Tirzepatide (Mounjaro®) is a novel dual-action drug combining GIP and GLP-1 receptor agonism to treat Type 2 Diabetes (T2D). Approved by the FDA in 2022, it achieves substantial reductions in both HbA1c and body weight, surpassing results from traditional GLP-1-based treatments. Clinical trials highlight its impact on T2D patients, with the SURPASS-4 study showing lower mortality during COVID-19 when compared to insulin glargine. With a favorable safety profile, Tirzepatide presents a promising, well-tolerated option in the management of complex metabolic conditions, including potential future uses in obesity treatment.
Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.
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Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.
Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.
Gallwitz, B., 2022. Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity. Frontiers in Endocrinology.