Tesofensine is a drug used to treat obesity by acting on three neurotransmitters; dopamine serotonin and norepinephrine. It helps regulate appetite and promote weight loss in both animals and humans also studies have shown that besides curbing hunger pangs tesofensine also boosts energy expenditure for those on a high fat diet. Its focuses on neurons in the hypothalamus, which could lead to changes, in eating habits.
Perez, C.I., Luis-Islas, J., Lopez, A., Diaz, X., Molina, O., Arroyo, B., Moreno, M.G., Gil Lievana, E., Fonseca, E., Castañeda-Hernández, G. and Gutierrez, R., 2024. Tesofensine, a novel antiobesity drug, silences GABAergic hypothalamic neurons. PLoS One
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Perez, C.I., Luis-Islas, J., Lopez, A., Diaz, X., Molina, O., Arroyo, B., Moreno, M.G., Gil Lievana, E., Fonseca, E., Castañeda-Hernández, G. and Gutierrez, R., 2024. Tesofensine, a novel antiobesity drug, silences GABAergic hypothalamic neurons. PLoS One
Perez, C.I., Luis-Islas, J., Lopez, A., Diaz, X., Molina, O., Arroyo, B., Moreno, M.G., Gil Lievana, E., Fonseca, E., Castañeda-Hernández, G. and Gutierrez, R., 2024. Tesofensine, a novel antiobesity drug, silences GABAergic hypothalamic neurons. PLoS One
Perez, C.I., Luis-Islas, J., Lopez, A., Diaz, X., Molina, O., Arroyo, B., Moreno, M.G., Gil Lievana, E., Fonseca, E., Castañeda-Hernández, G. and Gutierrez, R., 2024. Tesofensine, a novel antiobesity drug, silences GABAergic hypothalamic neurons. PLoS One
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