Selank is a peptide known for its calming, anxiolytic effects, similar to those of benzodiazepines, achieved by enhancing the inhibitory action of GABA via modulation of GABAA receptors. Studies in neuroblastoma cells indicate that while Selank alone does not alter the gene expression within the GABAergic system, it significantly influences GABA’s effects on gene expression when combined, making it a promising option for anxiety treatment. Additionally, Selank enhances gene modulation when used alongside olanzapine, underscoring its potential to support GABAergic neurotransmission in complex therapeutic settings.
Filatova, E., Kasian, A., Kolomin, T., Rybalkina, E., Alieva, A., Andreeva, L., Limborska, S., Myasoedov, N., Pavlova, G., Slominsky, P., Shadrina, M. (2017). GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells. Front Pharmacol.
Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.
For detailed information about Selank 10 by Ultima Pharmaceuticals, consult with your doctor or healthcare professional.
Filatova, E., Kasian, A., Kolomin, T., Rybalkina, E., Alieva, A., Andreeva, L., Limborska, S., Myasoedov, N., Pavlova, G., Slominsky, P., Shadrina, M. (2017). GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells. Front Pharmacol.
Filatova, E., Kasian, A., Kolomin, T., Rybalkina, E., Alieva, A., Andreeva, L., Limborska, S., Myasoedov, N., Pavlova, G., Slominsky, P., Shadrina, M. (2017). GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells. Front Pharmacol.
Filatova, E., Kasian, A., Kolomin, T., Rybalkina, E., Alieva, A., Andreeva, L., Limborska, S., Myasoedov, N., Pavlova, G., Slominsky, P., Shadrina, M. (2017). GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells. Front Pharmacol.