A phase 3 trial compared triptorelin pamoate PR 3-month to triptorelin acetate PR 1-month in Chinese women with endometriosis. Both formulations achieved chemical castration (E2 ≤ 184 pmol/L) in over 98% of patients by week 12 and significantly reduced endometriosis-related pain. The 3-month formulation demonstrated noninferiority, with no new safety concerns, making it a valid alternative for reducing injection frequency and improving treatment convenience for patients.
Li, X., Li, H., Shi, H., Li, X., Zhou, R., Lu, D., Cai, Y., Zhou, Y., Cabri, P., Shi, X., Pedret-Dunn, A., and Leng, J., 2022. Assessment of two formulations of triptorelin in Chinese patients with endometriosis: A phase 3, randomized controlled trial. Advances in Therapy.
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For detailed information about Ultima-Triptorelin 2 by Ultima Pharmaceuticals, consult with your doctor or healthcare professional.
Li, X., Li, H., Shi, H., Li, X., Zhou, R., Lu, D., Cai, Y., Zhou, Y., Cabri, P., Shi, X., Pedret-Dunn, A., and Leng, J., 2022. Assessment of two formulations of triptorelin in Chinese patients with endometriosis: A phase 3, randomized controlled trial. Advances in Therapy.
Li, X., Li, H., Shi, H., Li, X., Zhou, R., Lu, D., Cai, Y., Zhou, Y., Cabri, P., Shi, X., Pedret-Dunn, A., and Leng, J., 2022. Assessment of two formulations of triptorelin in Chinese patients with endometriosis: A phase 3, randomized controlled trial. Advances in Therapy.
Li, X., Li, H., Shi, H., Li, X., Zhou, R., Lu, D., Cai, Y., Zhou, Y., Cabri, P., Shi, X., Pedret-Dunn, A., and Leng, J., 2022. Assessment of two formulations of triptorelin in Chinese patients with endometriosis: A phase 3, randomized controlled trial. Advances in Therapy.
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