Ipamorelin’s effect on body composition has sparked interest among researchers. Unlike GH, which may cause consistent weight gain, ipamorelin leads to rapid weight increases in the first 1-2 weeks, with levels stabilizing over time. In animal studies, this peptide caused significant early weight gain, notably in GH-deficient mice, without affecting organs like the liver. This makes ipamorelin appealing in settings where initial rapid mass gain and stabilization are preferable, positioning it as a highly controlled option for managing body weight and fat distribution.
Sinha, D.K., Balasubramanian, A., Tatem, A.J., Rivera-Mirabal, J., Yu, J., Kovac, J., Pastuszak, A.W. and Lipshultz, L.I., 2020. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Translational Andrology and Urology.
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Sinha, D.K., Balasubramanian, A., Tatem, A.J., Rivera-Mirabal, J., Yu, J., Kovac, J., Pastuszak, A.W. and Lipshultz, L.I., 2020. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Translational Andrology and Urology.
Sinha, D.K., Balasubramanian, A., Tatem, A.J., Rivera-Mirabal, J., Yu, J., Kovac, J., Pastuszak, A.W. and Lipshultz, L.I., 2020. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Translational Andrology and Urology.
Sinha, D.K., Balasubramanian, A., Tatem, A.J., Rivera-Mirabal, J., Yu, J., Kovac, J., Pastuszak, A.W. and Lipshultz, L.I., 2020. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Translational Andrology and Urology.