Ipamorelin is a synthetic pentapeptide that acts as a selective agonist for the ghrelin/growth hormone secretagogue (GHS) receptor pathway. Mimicking natural ghrelin, it binds to the GHSR 1a receptor, promoting growth hormone (GH) release from the pituitary gland and influencing anabolic processes like appetite regulation and fat metabolism. Studies highlight ipamorelin's potential to improve gastric motility, particularly concerning postoperative ileus. Research shows significant weight gain in both GH-deficient and intact mice without causing the organomegaly linked to traditional GH therapies. Adverse effects are infrequent; however, further research is necessary to understand long-term implications, especially for hypogonadal individuals.
Sinha, D.K., Balasubramanian, A., Tatem, A.J., Rivera-Mirabal, J., Yu, J., Kovac, J., Pastuszak, A.W. and Lipshultz, L.I., 2020. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Translational Andrology and Urology.
Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.
For detailed information about IPAMORELIN by Deus Medical, consult with your doctor or healthcare professional.
Sinha, D.K., Balasubramanian, A., Tatem, A.J., Rivera-Mirabal, J., Yu, J., Kovac, J., Pastuszak, A.W. and Lipshultz, L.I., 2020. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Translational Andrology and Urology.
Sinha, D.K., Balasubramanian, A., Tatem, A.J., Rivera-Mirabal, J., Yu, J., Kovac, J., Pastuszak, A.W. and Lipshultz, L.I., 2020. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Translational Andrology and Urology.
Sinha, D.K., Balasubramanian, A., Tatem, A.J., Rivera-Mirabal, J., Yu, J., Kovac, J., Pastuszak, A.W. and Lipshultz, L.I., 2020. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Translational Andrology and Urology.
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