My account
Injectables Orals Peptides Human Growth Hormone SARMs
Sign in
A
Anastrozole
B
Bacteriostatic water Boldenone undecylenate
C
Clenbuterol Clomiphene citrate Cabergoline
D
Drostanolone enanthate Drostanolone propionate Dehydroepiandrosterone (DHEA)
E
Erythropoietin Exemestane
F
Fluoxymesterone
H
Human chorionic gonadotropin Human growth hormone (HGH)
L
Liothyronine sodium
M
Mecasermin Meldonium Mesterolone Methandienone Methenolone acetate Methenolone enanthate Melanotan-2
N
Nandrolone decanoate Nandrolone phenylpropionate
O
Oxandrolone Oxymetholone
S
Sildenafil citrate Stanozolol
T
Trenbolone enanthate Trestolone acetate Trenbolone acetate Testosterone undecanoate Testosterone propionate Testosterone base and suspension Tadalafil citrate Testosterone cypionate Testosterone enanthate Tamoxifen citrate Turinabol
Y
Yohimbine
Show 164 results
Manufacturers
Categories
Substances
Disagree
Home Driada Medical Driada Medical
MOTS-C
MOTS-C - Driada Medical

MOTS-C - Driada Medical

Brand:
Driada Medical
Category:
Peptides
Substance:
MOTS-c
Package:
10 mg
Price:
0
See options
Product Overview
Identified in 2015, MOTS-c is a 16-amino-acid mitochondrial peptide that regulates key metabolic functions despite being translated in the cytoplasm. It enhances insulin sensitivity, activates AMPK, and influences energy use, particularly in skeletal muscle, adipose tissue, and the pancreas. MOTS-c levels drop in obesity, linking it to metabolic dysfunction. It promotes thermogenesis, preserves muscle under stress, and may protect pancreatic cells. These roles make it a strong candidate for future therapies targeting diabetes, obesity, and age-related metabolic decline.
References:

Bień, J., Pruszyńska-Oszmałek, E., Kołodziejski, P., Leciejewska, N., Szczepankiewicz, D., & Sassek, M. (2024) 'MOTS-c regulates pancreatic alpha and beta cell functions in vitro', Histochemistry and Cell Biology.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about MOTS-C by Driada Medical, consult with your doctor or healthcare professional.

Explore More Products
Reviews
Leave Review
FAQ
What is MOTS-c and how was it discovered?
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded by a short ORF in the 12S rRNA. Researchers first identified MOTS-c via in silico analysis in 2015.
References:

Bień, J., Pruszyńska-Oszmałek, E., Kołodziejski, P., Leciejewska, N., Szczepankiewicz, D., & Sassek, M. (2024) 'MOTS-c regulates pancreatic alpha and beta cell functions in vitro', Histochemistry and Cell Biology.

How does MOTS-c affect insulin sensitivity?
MOTS-c activates the AMPK pathway in muscle and liver cells, counteracting diet-induced insulin resistance and improving glucose uptake in beta cells.
References:

Bień, J., Pruszyńska-Oszmałek, E., Kołodziejski, P., Leciejewska, N., Szczepankiewicz, D., & Sassek, M. (2024) 'MOTS-c regulates pancreatic alpha and beta cell functions in vitro', Histochemistry and Cell Biology.

Why are MOTS-c levels important in obesity?
Obese individuals have lower circulating MOTS-c levels, suggesting that reduced MOTS-c contributes to metabolic imbalance and insulin resistance.
References:

Bień, J., Pruszyńska-Oszmałek, E., Kołodziejski, P., Leciejewska, N., Szczepankiewicz, D., & Sassek, M. (2024) 'MOTS-c regulates pancreatic alpha and beta cell functions in vitro', Histochemistry and Cell Biology.