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Diovan 320
Diovan 320 - Novartis

Diovan 320 - Novartis

Brand:
Category:
Substance:
Dosage:
320 mg/tab
Package:
28 tablets
Price:
$70.00 - $70.00
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Product Overview

Valsartan’s therapeutic benefits extend to nephroprotection, particularly in diabetic patients. It reduces albuminuria and protects kidney function by mitigating oxidative stress and improving vascular health. By lowering AGE-related inflammation and reducing ROS production, valsartan prevents damage to endothelial cells and vascular smooth muscle. Clinical studies show that valsartan is well-tolerated, with a safety profile similar to placebo, and avoids common side effects like cough associated with ACE inhibitors. This makes it a reliable choice for patients with cardiovascular and renal risks.

References:

Mil, K.M., Gryciuk, M.E., Pawlukianiec, C., Żendzian-Piotrowska, M., Ładny, J.R., Zalewska, A., and Maciejczyk, M., 2021. Pleiotropic properties of valsartan: Do they result from the antiglycooxidant activity? Literature review and in vitro study. Oxidative Medicine and Cellular Longevity.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about Diovan 320 by Novartis, consult with your doctor or healthcare professional.

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FAQ
How does valsartan compare to antioxidants?
Valsartan’s effects on oxidative stress and glycation are comparable to known antioxidants like N-acetylcysteine and lipoic acid, making it a multifaceted therapeutic option.
References:

Mil, K.M., Gryciuk, M.E., Pawlukianiec, C., Żendzian-Piotrowska, M., Ładny, J.R., Zalewska, A., and Maciejczyk, M., 2021. Pleiotropic properties of valsartan: Do they result from the antiglycooxidant activity? Literature review and in vitro study. Oxidative Medicine and Cellular Longevity.

What are the pharmacokinetics of valsartan?
Valsartan is rapidly absorbed but has low bioavailability (~25%). It is highly protein-bound and primarily excreted via bile after hepatic metabolism.
References:

Mil, K.M., Gryciuk, M.E., Pawlukianiec, C., Żendzian-Piotrowska, M., Ładny, J.R., Zalewska, A., and Maciejczyk, M., 2021. Pleiotropic properties of valsartan: Do they result from the antiglycooxidant activity? Literature review and in vitro study. Oxidative Medicine and Cellular Longevity.

Does valsartan have anti-inflammatory effects?
Yes, valsartan reduces inflammatory pathways by lowering AGE-RAGE interactions and NF-κB activation, which are linked to oxidative stress and cardiovascular damage.
References:

Mil, K.M., Gryciuk, M.E., Pawlukianiec, C., Żendzian-Piotrowska, M., Ładny, J.R., Zalewska, A., and Maciejczyk, M., 2021. Pleiotropic properties of valsartan: Do they result from the antiglycooxidant activity? Literature review and in vitro study. Oxidative Medicine and Cellular Longevity.