As a multifaceted therapeutic agent, valsartan goes beyond blood pressure control to address oxidative and glycation stress. It has been shown to reduce oxidative damage and AGE formation, preventing endothelial dysfunction and arterial stiffness. Its safety and efficacy in reducing cardiovascular risks are well-established, with significant benefits for diabetic and hypertensive patients. The drug’s dual action as an AT1 receptor blocker and antiglycooxidant underscores its value in treating a broad range of conditions linked to oxidative stress and protein glycation. This positions valsartan as an innovative and comprehensive option in modern therapy.
Mil, K.M., Gryciuk, M.E., Pawlukianiec, C., Żendzian-Piotrowska, M., Ładny, J.R., Zalewska, A., and Maciejczyk, M., 2021. Pleiotropic properties of valsartan: Do they result from the antiglycooxidant activity? Literature review and in vitro study. Oxidative Medicine and Cellular Longevity.
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Mil, K.M., Gryciuk, M.E., Pawlukianiec, C., Żendzian-Piotrowska, M., Ładny, J.R., Zalewska, A., and Maciejczyk, M., 2021. Pleiotropic properties of valsartan: Do they result from the antiglycooxidant activity? Literature review and in vitro study. Oxidative Medicine and Cellular Longevity.
Mil, K.M., Gryciuk, M.E., Pawlukianiec, C., Żendzian-Piotrowska, M., Ładny, J.R., Zalewska, A., and Maciejczyk, M., 2021. Pleiotropic properties of valsartan: Do they result from the antiglycooxidant activity? Literature review and in vitro study. Oxidative Medicine and Cellular Longevity.
Mil, K.M., Gryciuk, M.E., Pawlukianiec, C., Żendzian-Piotrowska, M., Ładny, J.R., Zalewska, A., and Maciejczyk, M., 2021. Pleiotropic properties of valsartan: Do they result from the antiglycooxidant activity? Literature review and in vitro study. Oxidative Medicine and Cellular Longevity.