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Home Sigma Pharmaceuticals Sigma Pharmaceuticals
ANDROXAL 12.5
ANDROXAL 12.5 - Sigma Pharmaceuticals

ANDROXAL 12.5 - Sigma Pharmaceuticals

Brand:
Sigma Pharmaceuticals
Category:
Orals
Substance:
Enclomiphene citrate
Dosage:
12.5 mg/tab
Package:
50 tablets
Price:
$67.00 - $67.00
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Product Overview

Enclomiphene citrate is identified in the literature as the trans-isomer of clomiphene, possessing distinct pharmacological properties. It acts as a selective estrogen receptor modulator (SERM), but unlike its counterpart zuclomiphene, enclomiphene shows stronger anti-estrogenic activity. Its emergence was tied to the differentiation of clomiphene's isomers for therapeutic targeting. The isomeric separation allowed researchers to refine its use in stimulating endogenous testosterone, particularly in cases of male hypogonadism.

References:

Wiehle, R., Cunningham, G.R., Pitteloud, N., Wike, J., Hsu, K., Fontenot, G.K., Rosner, M., Dwyer, A. and Podolski, J., 2013. Testosterone restoration using enclomiphene citrate in men with secondary hypogonadism: a pharmacodynamic and pharmacokinetic study. BJU International. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155868/

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about ANDROXAL 12.5 by Sigma Pharmaceuticals, consult with your doctor or healthcare professional.

Products
Active Substances
  • Enclomiphene citrate
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ANDROXAL
Sigma Pharmaceuticals
International
$67.00
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FAQ
Why is enclomiphene citrate suitable for men concerned about fertility?
Enclomiphene citrate increases testosterone without suppressing LH and FSH, helping to maintain natural sperm production.
References:

Wiehle, R., Cunningham, G.R., Pitteloud, N., Wike, J., Hsu, K., Fontenot, G.K., Rosner, M., Dwyer, A. and Podolski, J., 2013. Testosterone restoration using enclomiphene citrate in men with secondary hypogonadism: a pharmacodynamic and pharmacokinetic study. BJU International. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155868/

Does enclomiphene citrate offer more stable testosterone levels than gels?
Yes, enclomiphene citrate provides a consistent 24-hour testosterone profile with both morning and evening elevations, unlike transdermal options.
References:

Wiehle, R., Cunningham, G.R., Pitteloud, N., Wike, J., Hsu, K., Fontenot, G.K., Rosner, M., Dwyer, A. and Podolski, J., 2013. Testosterone restoration using enclomiphene citrate in men with secondary hypogonadism: a pharmacodynamic and pharmacokinetic study. BJU International. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155868/

How does enclomiphene citrate work differently from testosterone replacement?
Enclomiphene citrate acts by blocking estrogen receptors, triggering the hypothalamus to release LH and FSH, thereby increasing natural testosterone production.
References:

Wiehle, R., Cunningham, G.R., Pitteloud, N., Wike, J., Hsu, K., Fontenot, G.K., Rosner, M., Dwyer, A. and Podolski, J., 2013. Testosterone restoration using enclomiphene citrate in men with secondary hypogonadism: a pharmacodynamic and pharmacokinetic study. BJU International. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155868/