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Injectables Orals Peptides Human Growth Hormone SARMs

A

Anastrozole

B

Bacteriostatic water Boldenone undecylenate

C

Clenbuterol Clomiphene citrate Cabergoline

D

Drostanolone enanthate Drostanolone propionate Dehydroepiandrosterone (DHEA)

E

Erythropoietin Exemestane

F

Fluoxymesterone

H

Human chorionic gonadotropin Human growth hormone

L

Liothyronine sodium

M

Mecasermin Meldonium Mesterolone Methandienone Methenolone acetate Methenolone enanthate Melanotan-2

N

Nandrolone decanoate Nandrolone phenylpropionate

O

Oxandrolone Oxymetholone

S

Sildenafil citrate Stanozolol

T

Trenbolone enanthate Trestolone acetate Trenbolone acetate Testosterone undecanoate Testosterone propionate Testosterone base and suspension Tadalafil citrate Testosterone cypionate Testosterone enanthate Tamoxifen citrate Turinabol

Y

Yohimbine

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Telmisartan

Telmisartan

A-Z

Boehringer Ingelheim

Substance Overview and History

Primarily known as an antihypertensive agent, telmisartan has recently gained attention for its possible anti cancer effects, specifically against esophageal squamous cell carcinoma (ESCC). Works by halting the cell cycle at the S-phase, which stops cancer cells from multiplying. This lowers the concentration of essential proteins that facilitate cell growth. In result telmisartan could be a valuable option in cancer treatment, especially for those affected by ESCC.

References:

Matsui, T., Chiyo, T., Kobara, H., Fujihara, S., Fujita, K., Namima, D., Nakahara, M., Kobayashi, N., Nishiyama, N., Yachida, T., Morishita, A., Iwama, H., and Masaki, T. (2019) Telmisartan inhibits cell proliferation and tumor growth of esophageal squamous cell carcinoma by inducing S-phase arrest in vitro and in vivo', International Journal of Molecular Sciences.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For more details consult with your doctor or healthcare professional.

FAQ

What is telmisartan, and what is its primary use?

Telmisartan is an ARB used mainly to treat high blood pressure.

References:

Matsui, T., Chiyo, T., Kobara, H., Fujihara, S., Fujita, K., Namima, D., Nakahara, M., Kobayashi, N., Nishiyama, N., Yachida, T., Morishita, A., Iwama, H., and Masaki, T. (2019) Telmisartan inhibits cell proliferation and tumor growth of esophageal squamous cell carcinoma by inducing S-phase arrest in vitro and in vivo', International Journal of Molecular Sciences.

How does telmisartan affect esophageal squamous cell carcinoma (ESCC)?

Telmisartan inhibits the growth of ESCC cells and tumors by inducing S-phase arrest in the cell cycle.

References:

Matsui, T., Chiyo, T., Kobara, H., Fujihara, S., Fujita, K., Namima, D., Nakahara, M., Kobayashi, N., Nishiyama, N., Yachida, T., Morishita, A., Iwama, H., and Masaki, T. (2019) Telmisartan inhibits cell proliferation and tumor growth of esophageal squamous cell carcinoma by inducing S-phase arrest in vitro and in vivo', International Journal of Molecular Sciences.

What are the results in study on telmisartan’s antitumor effects?

Telmisartan has a dose dependent effect on reducing ESCC cell proliferation, primarily by inducing S-phase arrest.

References:

Matsui, T., Chiyo, T., Kobara, H., Fujihara, S., Fujita, K., Namima, D., Nakahara, M., Kobayashi, N., Nishiyama, N., Yachida, T., Morishita, A., Iwama, H., and Masaki, T. (2019) Telmisartan inhibits cell proliferation and tumor growth of esophageal squamous cell carcinoma by inducing S-phase arrest in vitro and in vivo', International Journal of Molecular Sciences.