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Sildenafil citrate

Sildenafil citrate - Page 3

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Substance Overview and History

Viagra is a medication also known as Sildenafil citrate that was created by Pfizer in 1989 as a type of inhibitor called a PDE5 inhibitor aimed at enhancing blood circulation through the NO/cGMP pathway, for heart related issues like angina or chest pain initially believed it might help with dysfunction (ED). However subsequent tests proved its effectiveness in treating ED which led to its approval by the FDA in 1998 since then Viagra has revolutionized the treatment of ED and has become an widely prescribed option, for millions of people worldwide.

References:

Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For more details consult with your doctor or healthcare professional.

FAQ
What is Sildenafil citrate?
Sildenafil citrate also known worldwide as Viagra, is a selective inhibitor of phosphodiesterase type 5(PDE5) used to treat erectile dysfunction(ED).
References:

Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.

When was Sildenafil citrate developed?
It was first synthesized by Pfizer in 1989 as part of a research project aimed at treating cardiovascular diseases like angina.
References:

Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.

How does Sildenafil citrate work?
Sildenafil works by inhibiting PDE5, enhancing the nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) pathway, leading to increased blood flow.
References:

Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.