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Pen-os 1000
Pen-os 1000 - Sandoz

Pen-os 1000 - Sandoz

Brand:
Category:
Substance:
Dosage:
1000 mg/tab
Package:
24 tablets
Price:
€35.00 - €35.00
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Product Overview
Addressing penicillin allergies is vital for optimizing antibiotic therapy in conditions like acute rheumatic fever (ARF) and rheumatic heart disease (RHD). While Benzathine penicillin G (BPG) is the standard for preventing RHD, many patients are unnecessarily labeled as penicillin-allergic, limiting treatment options. Testing reveals that most reported allergies are inactive or non-immunologic, allowing safe delabeling through low-dose oral challenges or skin testing. Correctly identifying penicillin allergies reduces inappropriate labeling, broadens therapeutic choices, and improves antimicrobial stewardship.
References:

Providencia, R., Aali, G., Zhu, F., Leas, B.F., Orrell, R., Ahmad, M., Bray, J.J.H., Pelone, F., Nass, P., Marijon, E., Cassandra, M., Celermajer, D.S. and Shokraneh, F., 2024. Penicillin allergy testing and delabeling for patients who are prescribed penicillin: A systematic review for a World Health Organization guideline. Clinical Reviews in Allergy & Immunology. 

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about Pen-os 1000 by Sandoz, consult with your doctor or healthcare professional.

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FAQ
What are the symptoms of penicillin allergy?
Penicillin allergies may cause immediate reactions like hives, swelling, or anaphylaxis, or delayed reactions such as rashes or serum sickness.
References:

Providencia, R., Aali, G., Zhu, F., Leas, B.F., Orrell, R., Ahmad, M., Bray, J.J.H., Pelone, F., Nass, P., Marijon, E., Cassandra, M., Celermajer, D.S. and Shokraneh, F., 2024. Penicillin allergy testing and delabeling for patients who are prescribed penicillin: A systematic review for a World Health Organization guideline. Clinical Reviews in Allergy & Immunology. 

Why is penicillin important in preventing RHD?
It is the primary antibiotic for preventing group A streptococcal infections that cause RHD.
References:

Providencia, R., Aali, G., Zhu, F., Leas, B.F., Orrell, R., Ahmad, M., Bray, J.J.H., Pelone, F., Nass, P., Marijon, E., Cassandra, M., Celermajer, D.S. and Shokraneh, F., 2024. Penicillin allergy testing and delabeling for patients who are prescribed penicillin: A systematic review for a World Health Organization guideline. Clinical Reviews in Allergy & Immunology. 

What impact does delabeling have on antibiotic use?
It expands treatment options and reduces unnecessary reliance on alternative antibiotics.
References:

Providencia, R., Aali, G., Zhu, F., Leas, B.F., Orrell, R., Ahmad, M., Bray, J.J.H., Pelone, F., Nass, P., Marijon, E., Cassandra, M., Celermajer, D.S. and Shokraneh, F., 2024. Penicillin allergy testing and delabeling for patients who are prescribed penicillin: A systematic review for a World Health Organization guideline. Clinical Reviews in Allergy & Immunology.