Penicillin plays a crucial role in treating bacterial infections and preventing complications of rheumatic heart disease, yet its utility is often hindered by misreported allergies. Globally, approximately 10% of patients self-report penicillin allergies, but true allergies are rare. Testing and delabeling processes, such as low-dose oral challenges, are safe and effective in most cases, allowing more patients access to this essential antibiotic. Strengthening routine allergy evaluations can optimize its use, especially in critical regions where ARF and RHD remain prevalent health concerns.
Providencia, R., Aali, G., Zhu, F., Leas, B.F., Orrell, R., Ahmad, M., Bray, J.J.H., Pelone, F., Nass, P., Marijon, E., Cassandra, M., Celermajer, D.S. and Shokraneh, F., 2024. Penicillin allergy testing and delabeling for patients who are prescribed penicillin: A systematic review for a World Health Organization guideline. Clinical Reviews in Allergy & Immunology.
Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.
For detailed information about Pen-os 1000 by Sandoz, consult with your doctor or healthcare professional.
Providencia, R., Aali, G., Zhu, F., Leas, B.F., Orrell, R., Ahmad, M., Bray, J.J.H., Pelone, F., Nass, P., Marijon, E., Cassandra, M., Celermajer, D.S. and Shokraneh, F., 2024. Penicillin allergy testing and delabeling for patients who are prescribed penicillin: A systematic review for a World Health Organization guideline. Clinical Reviews in Allergy & Immunology.
Providencia, R., Aali, G., Zhu, F., Leas, B.F., Orrell, R., Ahmad, M., Bray, J.J.H., Pelone, F., Nass, P., Marijon, E., Cassandra, M., Celermajer, D.S. and Shokraneh, F., 2024. Penicillin allergy testing and delabeling for patients who are prescribed penicillin: A systematic review for a World Health Organization guideline. Clinical Reviews in Allergy & Immunology.
Providencia, R., Aali, G., Zhu, F., Leas, B.F., Orrell, R., Ahmad, M., Bray, J.J.H., Pelone, F., Nass, P., Marijon, E., Cassandra, M., Celermajer, D.S. and Shokraneh, F., 2024. Penicillin allergy testing and delabeling for patients who are prescribed penicillin: A systematic review for a World Health Organization guideline. Clinical Reviews in Allergy & Immunology.