Studies in humans reinforced MT-II’s central proerectile effects. In one controlled trial, ten men with non-organic erectile dysfunction received MT-II doses, leading to erections in eight of the ten participants. Their erections averaged 38 minutes of 80% rigidity, a notable improvement over placebo. This response confirmed MT-II’s effectiveness in men with psychological, rather than physiological, erectile dysfunction. Although side effects like nausea and yawning were reported, these were dose-dependent and generally mild. MT-II’s ability to stimulate erections through central pathways without extensive side effects established it as a promising therapy.
King, S.H., Mayorov, A.V., Balse-Srinivasan, P., Hruby, V.J., Vanderah, T.W., and Wessells, H. (2007). Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry.
Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.
For detailed information about MELANOTAN II by Keifei Pharma, consult with your doctor or healthcare professional.
King, S.H., Mayorov, A.V., Balse-Srinivasan, P., Hruby, V.J., Vanderah, T.W., and Wessells, H. (2007). Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry.
King, S.H., Mayorov, A.V., Balse-Srinivasan, P., Hruby, V.J., Vanderah, T.W., and Wessells, H. (2007). Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry.
King, S.H., Mayorov, A.V., Balse-Srinivasan, P., Hruby, V.J., Vanderah, T.W., and Wessells, H. (2007). Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry.
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