Beyond tanning, MT-II’s influence on the melanocortinergic system extends to various physiological effects, including impacts on food intake, nerve regeneration, pain response, and sexual behavior. This is achieved through the compound’s binding with five melanocortin receptor subtypes derived from the POMC gene. Among these, MC4R is significant for its role in penile erection and libido modulation. MT-II’s ability to activate these receptors for both tanning and sexual function highlights the versatility of melanocortin agents. These properties have positioned MT-II as a unique tool in addressing erectile dysfunction through a mechanism distinct from traditional vasodilatory agents.
King, S.H., Mayorov, A.V., Balse-Srinivasan, P., Hruby, V.J., Vanderah, T.W., and Wessells, H. (2007). Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry.
Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.
For detailed information about MELANOTAN II by Euro-Pharmacies, consult with your doctor or healthcare professional.
King, S.H., Mayorov, A.V., Balse-Srinivasan, P., Hruby, V.J., Vanderah, T.W., and Wessells, H. (2007). Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry.
King, S.H., Mayorov, A.V., Balse-Srinivasan, P., Hruby, V.J., Vanderah, T.W., and Wessells, H. (2007). Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry.
King, S.H., Mayorov, A.V., Balse-Srinivasan, P., Hruby, V.J., Vanderah, T.W., and Wessells, H. (2007). Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry.