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Intex Stenabolic
Intex Stenabolic - Intex Pharma

Intex Stenabolic - Intex Pharma

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60 tablets
Price:
€74.00 - €74.00
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Product Overview
Stenabolic (SR9009) was initially developed to act on REV-ERB receptors but has shown significant anticancer effects in prostate cancer through a distinct mechanism. Research reveals that SR9009 suppresses the LXRα/FOXM1 pathway, a critical driver of PCS1 prostate cancer aggressiveness. In both in vitro and in vivo models, SR9009 treatment reduces tumor size, decreases cell migration, and promotes apoptosis while sparing normal tissues. This selective action presents a novel approach to targeting prostate cancer without the adverse effects associated with conventional androgen-targeted therapies .
References:

Xu, H., Zhang, J., Zheng, X., Tan, P., Xiong, X., Yi, X., Yang, Y., Wang, Y., Liao, D., Li, H., Wei, Q., Ai, J. and Yang, L., 2022. SR9009 inhibits lethal prostate cancer subtype 1 by regulating the LXRα/FOXM1 pathway independently of REV-ERBs. Cell Death & Disease.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about Intex Stenabolic by Intex Pharma, consult with your doctor or healthcare professional.

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FAQ
What subtype of prostate cancer does SR9009 target?
It is particularly effective against the highly aggressive PCS1 subtype.
References:

Xu, H., Zhang, J., Zheng, X., Tan, P., Xiong, X., Yi, X., Yang, Y., Wang, Y., Liao, D., Li, H., Wei, Q., Ai, J. and Yang, L., 2022. SR9009 inhibits lethal prostate cancer subtype 1 by regulating the LXRα/FOXM1 pathway independently of REV-ERBs. Cell Death & Disease.

Which pathway does SR9009 inhibit?
It disrupts the LXRα/FOXM1 pathway, a critical axis in prostate cancer progression.
References:

Xu, H., Zhang, J., Zheng, X., Tan, P., Xiong, X., Yi, X., Yang, Y., Wang, Y., Liao, D., Li, H., Wei, Q., Ai, J. and Yang, L., 2022. SR9009 inhibits lethal prostate cancer subtype 1 by regulating the LXRα/FOXM1 pathway independently of REV-ERBs. Cell Death & Disease.

Are there systemic side effects?
Animal studies indicate minimal systemic toxicity, suggesting a favorable safety profile.
References:

Xu, H., Zhang, J., Zheng, X., Tan, P., Xiong, X., Yi, X., Yang, Y., Wang, Y., Liao, D., Li, H., Wei, Q., Ai, J. and Yang, L., 2022. SR9009 inhibits lethal prostate cancer subtype 1 by regulating the LXRα/FOXM1 pathway independently of REV-ERBs. Cell Death & Disease.