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Dapoxetinos 30
Dapoxetinos 30 - Driada Medical

Dapoxetinos 30 - Driada Medical

Brand:
Driada Medical
Category:
Orals
Substance:
Dapoxetine
Dosage:
30 mg/tab
Package:
20 tablets
Price:
0
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Product Overview
Dapoxetine shows potential as a repurposed antiviral against ZIKV by inhibiting its RNA polymerase. Structural and SPR analysis confirmed selective binding with a Kd of 49.8 μM. Infected cell assays demonstrated dose-dependent reduction in ZIKV RNA and protein levels, with potent EC50 values and minimal toxicity. Clinically approved and well-tolerated, dapoxetine could achieve effective plasma levels safely. Its broad action on RNA polymerases also suggests utility against other RNA viruses, warranting further preclinical and in vivo exploration.
References:

Nunes, K.P., 2012. Erectile Dysfunction: Disease-Associated Mechanisms and Novel Insights Into Therapy.  (2012). Croatia: IntechOpen.

Klein, E.D., 2024. Dapoxetine Comprehensive Guide. Amazon Digital Services LLC - Kdp

Balon, R. and Segraves, R.T., 2009. Clinical Manual of Sexual Disorders. United States: American Psychiatric Publishing. 

Knights, K., Rowland, A. and Darroch, S., 2018. Pharmacology for Health Professionals. EBook. United States: Elsevier Health Sciences. 

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about Dapoxetinos 30 by Driada Medical, consult with your doctor or healthcare professional.

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FAQ
What laboratory methods confirmed Dapoxetine's antiviral action?
Dapoxetine’s ZIKV inhibition was validated by SPR assays, Western blot, and immunofluorescence studies.
References:

Zhang, B., Yu, J., Zhu, G., Huang, Y., Zhang, K., Xiao, X., He, W., Yuan, J., Gao, X. (2023) 'Dapoxetine, a Selective Serotonin Reuptake Inhibitor, Suppresses Zika Virus Infection In Vitro', Molecules. 

Does Dapoxetine have potential against other viruses?
Yes, Dapoxetine may act broadly against RNA viruses due to its RNA polymerase targeting mechanism.
References:

Zhang, B., Yu, J., Zhu, G., Huang, Y., Zhang, K., Xiao, X., He, W., Yuan, J., Gao, X. (2023) 'Dapoxetine, a Selective Serotonin Reuptake Inhibitor, Suppresses Zika Virus Infection In Vitro', Molecules. 

Why is Dapoxetine considered promising for emerging infections?
Dapoxetine’s rapid action, safety, and broad RNA virus inhibition make it a candidate for repurposing.
References:

Zhang, B., Yu, J., Zhu, G., Huang, Y., Zhang, K., Xiao, X., He, W., Yuan, J., Gao, X. (2023) 'Dapoxetine, a Selective Serotonin Reuptake Inhibitor, Suppresses Zika Virus Infection In Vitro', Molecules.