My account
Injectables Orals Peptides Human Growth Hormone SARMs
Sign in
A
Anastrozole
B
Bacteriostatic water Boldenone undecylenate
C
Clenbuterol Clomiphene citrate Cabergoline
D
Drostanolone enanthate Drostanolone propionate Dehydroepiandrosterone (DHEA)
E
Erythropoietin Exemestane
F
Fluoxymesterone
H
Human chorionic gonadotropin Human growth hormone
L
Liothyronine sodium
M
Mecasermin Meldonium Mesterolone Methandienone Methenolone acetate Methenolone enanthate Melanotan-2
N
Nandrolone decanoate Nandrolone phenylpropionate
O
Oxandrolone Oxymetholone
S
Sildenafil citrate Stanozolol
T
Trenbolone enanthate Trestolone acetate Trenbolone acetate Testosterone undecanoate Testosterone propionate Testosterone base and suspension Tadalafil citrate Testosterone cypionate Testosterone enanthate Tamoxifen citrate Turinabol
Y
Yohimbine
Show 164 results
Manufacturers
Categories
Substances
Disagree
Home Bayer Bayer
Avelox 400
Avelox 400 - Bayer

Avelox 400 - Bayer

Brand:
Bayer
Category:
Orals
Substance:
Moxifloxacin
Dosage:
400 mg/tab
Package:
5 tablets, 7 tablets
Price:
$40.00 - $40.00
See options
Product Overview

Moxifloxacin plays a crucial role in managing drug-resistant tuberculosis by leveraging its unique ability to target bacterial DNA and oxidative processes. It generates reactive oxygen species (ROS) within Mycobacterium tuberculosis, leading to lethal oxidative stress and cellular damage. The drug also influences metabolic pathways, including NADH-reductive stress, further amplifying its bactericidal properties. Adjunct therapies, such as N-acetyl cysteine, have been shown to enhance moxifloxacin's effectiveness and limit resistance emergence, making it a key agent in shortening TB treatment durations.

References:

Shee, S., Singh, S., Tripathi, A., Thakur, C., Kumar T, A., Das, M., Yadav, V., Kohli, S., Rajmani, R. S., Chandra, N., Chakrapani, H., Drlica, K., & Singh, A. (2022). Moxifloxacin-Mediated Killing of Mycobacterium tuberculosis Involves Respiratory Downshift, Reductive Stress, and Accumulation of Reactive Oxygen Species. Antimicrobial Agents and Chemotherapy.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about Avelox 400 by Bayer, consult with your doctor or healthcare professional.

Products
Active Substances
  • Moxifloxacin
 About Product
Avelox 400 mg 7 Tablets Bayer
Bayer
International
$40.00
Info
Show more
Explore More Products
Reviews
Leave Review
FAQ
What are the side effects of Moxifloxacin?
Common side effects include nausea, diarrhea, headache, and dizziness. Rare but serious effects may involve tendon damage, QT prolongation, and central nervous system disturbances.
References:

Shee, S., Singh, S., Tripathi, A., Thakur, C., Kumar T, A., Das, M., Yadav, V., Kohli, S., Rajmani, R. S., Chandra, N., Chakrapani, H., Drlica, K., & Singh, A. (2022). Moxifloxacin-Mediated Killing of Mycobacterium tuberculosis Involves Respiratory Downshift, Reductive Stress, and Accumulation of Reactive Oxygen Species. Antimicrobial Agents and Chemotherapy.

Can Moxifloxacin resistance develop?
Yes, resistance can emerge, especially if the drug is not used properly or combined with other therapies. Combining Moxifloxacin with agents like N-acetyl cysteine can enhance its efficacy and reduce resistance risks.
References:

Shee, S., Singh, S., Tripathi, A., Thakur, C., Kumar T, A., Das, M., Yadav, V., Kohli, S., Rajmani, R. S., Chandra, N., Chakrapani, H., Drlica, K., & Singh, A. (2022). Moxifloxacin-Mediated Killing of Mycobacterium tuberculosis Involves Respiratory Downshift, Reductive Stress, and Accumulation of Reactive Oxygen Species. Antimicrobial Agents and Chemotherapy.

What makes Moxifloxacin different from other fluoroquinolones?
Moxifloxacin is more potent and effective against Mycobacterium tuberculosis. It also suppresses bacterial respiration, increasing its lethal effects, unlike earlier quinolones such as ciprofloxacin or ofloxacin.
References:

Shee, S., Singh, S., Tripathi, A., Thakur, C., Kumar T, A., Das, M., Yadav, V., Kohli, S., Rajmani, R. S., Chandra, N., Chakrapani, H., Drlica, K., & Singh, A. (2022). Moxifloxacin-Mediated Killing of Mycobacterium tuberculosis Involves Respiratory Downshift, Reductive Stress, and Accumulation of Reactive Oxygen Species. Antimicrobial Agents and Chemotherapy.