Mechano growth factor - Page 2

Mechano Growth Factor (MGF) is a hormone related to growth processes, first identified in 1996 by Goldspink and colleagues. It is a splice variant of Insulin-Like Growth Factor 1 (IGF-1), primarily produced in muscle tissue following mechanical strain, such as resistance exercise. MGF triggers some of the early changes within cells that support repair and growth. The satellite cell cycle, which MGF activates, is crucial for ongoing hypertrophy. Satellite cells provide additional nuclei to expanding muscle fibers, allowing them to handle increased size. Without this process, muscle growth halts. MGF attracts attention in the bodybuilding community because it plays a part, in converting exertions into signals that promote muscle repair and growth. 

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