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Follistatin

Follistatin

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Substance Overview and History

Identified in 1987 while studying inhibin, Follistatin is a glycosylated protein that modulates hormone activity and promotes muscle growth by binding and inhibiting activin and myostatin. Has two primary isoforms, FS288 and FS315, differing in biological potency. Regulatory protein is essential in reproductive processes its also helps with muscle mass regulation. As per research Follistatin is very potential therapeutic agent for degenerative muscle conditions.

References:

Ledger, W. (2001). Inhibin, Activin, and Follistatin in Human Reproductive Physiology. Singapore: Imperial College Press.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For more details consult with your doctor or healthcare professional.

FAQ
What is Follistatin?
Its a glycosylated polypeptide that regulates hormone activity by binding and neutralizing proteins like activin and myostatin.
References:

Ledger, W. (2001). Inhibin, Activin, and Follistatin in Human Reproductive Physiology. Singapore: Imperial College Press.

How does Follistatin exaclty work?
Follistatin binds to activin and myostatin, neutralizing their effects and in result helps to regulate cell growth, muscle development, and hormonal balance.
References:

Ledger, W. (2001). Inhibin, Activin, and Follistatin in Human Reproductive Physiology. Singapore: Imperial College Press.

What role in muscle growth Follistatin has?
Follistatin inhibits myostatin, it is a protein that limits muscle growth, promoting increased muscle mass and tissue development.
References:

Ledger, W. (2001). Inhibin, Activin, and Follistatin in Human Reproductive Physiology. Singapore: Imperial College Press.