Originally researched for angina, Sildenafil citrate emerged as a breakthrough for erectile dysfunction, offering effective relief by selectively inhibiting PDE5. This action preserves cGMP levels within smooth muscle cells, enhancing vasodilation and blood flow. Approved by the FDA in 1998, Viagra quickly established itself as the go-to therapy for ED, outperforming alternatives with its combination of potency, safety, and minimal side effects. Its introduction transformed ED treatment, and today, Sildenafil remains the gold standard, with millions benefiting from its clinical effectiveness.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.
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Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.