Sildenafil citrate, better known as Viagra, is a selective phosphodiesterase type 5 (PDE5) inhibitor that acts through the nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) pathway to treat erectile dysfunction (ED). Originally synthesized in 1989 at Pfizer's Sandwich laboratories, it was developed to prevent cGMP breakdown, effectively relaxing smooth muscle tissue and increasing blood flow. Although initially aimed at treating angina, Viagra demonstrated notable efficacy in managing ED, leading to its approval in 1998. Today, Viagra is recognized worldwide for its effectiveness in over 20 million users, cementing its place as the gold standard in ED therapy.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.
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For detailed information about SILDEPEX 100 by Sixpex, consult with your doctor or healthcare professional.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.
Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.