Delta Sleep-Inducing Peptide (DSIP) was first isolated in 1977 by the Schoenenberger–Monnier group from the cerebral venous blood of rabbits. Initially studied for its sleep-promoting effects, DSIP has since shown broader physiological roles, including stress adaptation, neuroprotection, and hormonal regulation. It reduces corticotropin, stimulates growth hormone release, and normalizes brain metabolism under stress. DSIP also protects neurons in ischemic conditions, improves blood flow, and exhibits anticonvulsant properties, making it a potential therapeutic agent for neurological disorders.
Tukhovskaya, E.A., Ismailova, A.M., Shaykhutdinova, E.R., Slashcheva, G.A., Prudchenko, I.A., Mikhaleva, I.I., Khokhlova, O.N., Murashev, A.N., and Ivanov, V.T., 2021. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules.
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For detailed information about DSIP by Beligas Pharmaceuticals, consult with your doctor or healthcare professional.
Tukhovskaya, E.A., Ismailova, A.M., Shaykhutdinova, E.R., Slashcheva, G.A., Prudchenko, I.A., Mikhaleva, I.I., Khokhlova, O.N., Murashev, A.N., and Ivanov, V.T., 2021. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules.
Tukhovskaya, E.A., Ismailova, A.M., Shaykhutdinova, E.R., Slashcheva, G.A., Prudchenko, I.A., Mikhaleva, I.I., Khokhlova, O.N., Murashev, A.N., and Ivanov, V.T., 2021. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules.
Tukhovskaya, E.A., Ismailova, A.M., Shaykhutdinova, E.R., Slashcheva, G.A., Prudchenko, I.A., Mikhaleva, I.I., Khokhlova, O.N., Murashev, A.N., and Ivanov, V.T., 2021. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules.