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DHEA 300
DHEA 300 - Euro-Pharmacies

DHEA 300 - Euro-Pharmacies

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Category:
Substance:
Dosage:
300 mg/tab
Package:
50 tablets
Price:
€57.00 - €57.00
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Product Overview
DHEA, a precursor to androgens and estrogens, is gaining attention in assisted reproductive technology (ART) for its potential role in managing premature ovarian insufficiency (POI). Administered as an adjuvant in controlled ovarian hyperstimulation (COH) protocols, DHEA may enhance follicular development and improve clinical outcomes. Despite mixed evidence, studies indicate that DHEA can modulate apoptosis, inflammation, and oxidative stress, potentially activating the PTEN/PI3K/AKT pathway to support ovarian function, though its precise efficacy in POI remains under investigation.
References:

Cakir, C., Kuspinar, G., Aslan, K., Bozyigit, C., Kasapoglu, I., Dirican, M., Uncu, G., & Avci, B. (2024) Dehydroepiandrosterone modulates the PTEN/PI3K/AKT signaling pathway to alleviate 4-vinylcyclohexene diepoxide-induced premature ovarian insufficiency in rats, Experimental Animals. 

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about DHEA 300 by Euro-Pharmacies, consult with your doctor or healthcare professional.

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FAQ
What is the role of DHEA in POI treatment?
To support follicular development and hormone production.
References:

Cakir, C., Kuspinar, G., Aslan, K., Bozyigit, C., Kasapoglu, I., Dirican, M., Uncu, G., & Avci, B. (2024) Dehydroepiandrosterone modulates the PTEN/PI3K/AKT signaling pathway to alleviate 4-vinylcyclohexene diepoxide-induced premature ovarian insufficiency in rats, Experimental Animals. 

How does DHEA work in COH protocols?
It may modulate apoptosis and activate signaling pathways
References:

Cakir, C., Kuspinar, G., Aslan, K., Bozyigit, C., Kasapoglu, I., Dirican, M., Uncu, G., & Avci, B. (2024) Dehydroepiandrosterone modulates the PTEN/PI3K/AKT signaling pathway to alleviate 4-vinylcyclohexene diepoxide-induced premature ovarian insufficiency in rats, Experimental Animals. 

Is its efficacy proven?
Evidence is mixed; further studies are ongoing.
References:

Cakir, C., Kuspinar, G., Aslan, K., Bozyigit, C., Kasapoglu, I., Dirican, M., Uncu, G., & Avci, B. (2024) Dehydroepiandrosterone modulates the PTEN/PI3K/AKT signaling pathway to alleviate 4-vinylcyclohexene diepoxide-induced premature ovarian insufficiency in rats, Experimental Animals.