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Pitavastatin

Pitavastatin

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Substance Overview and History

Pitavastatin was approved in Japan in 2003 and in the U.S. in 2009 it has gained attention for its potential anticancer effects, particularly in types like triple negative breast cancer and ovarian cancer. It is a member of the statin family which is known for its cholesterol lowering properties and effectively reducing the risk of cardiovascular diseases. As per study results it may promote apoptosis and induce autophagy in cancer cells While exhibiting selective toxicity toward tumor cells over healthy ones, featuring its promising role in future cancer therapies.

References:

Chen, Y.-H., Wu, J.-X., Yang, S.-F., Wu, Y.-C. and Hsiao, Y.-H., 2024. Molecular mechanisms underlying the anticancer properties of pitavastatin against cervical cancer cells. International Journal of Molecular Sciences.

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FAQ
What is exactly is Pitavastatin?
A statin that lowers cholesterol levels and also lowers cardiovascular risk.
References:

Chen, Y.-H., Wu, J.-X., Yang, S.-F., Wu, Y.-C. and Hsiao, Y.-H., 2024. Molecular mechanisms underlying the anticancer properties of pitavastatin against cervical cancer cells. International Journal of Molecular Sciences.

When was Pitavastatin approved?
Approved in Japan in 2003 and the U.S. in 2009.
References:

Chen, Y.-H., Wu, J.-X., Yang, S.-F., Wu, Y.-C. and Hsiao, Y.-H., 2024. Molecular mechanisms underlying the anticancer properties of pitavastatin against cervical cancer cells. International Journal of Molecular Sciences.

How exactly Pitavastatin helps in cancer treatment?
It triggers programmed cell death and promotes the removal of damaged cells in cancer cells.
References:

Chen, Y.-H., Wu, J.-X., Yang, S.-F., Wu, Y.-C. and Hsiao, Y.-H., 2024. Molecular mechanisms underlying the anticancer properties of pitavastatin against cervical cancer cells. International Journal of Molecular Sciences.