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Nandrolone undecanoate

Nandrolone undecanoate

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Substance Overview and History

Nandrolone undecanoate is a long-acting esterified form of the anabolic–androgenic steroid nandrolone, derived from testosterone. Known for its powerful anabolic effects, it binds to androgen receptors to enhance protein synthesis, muscle recovery, and skeletal repair. Clinically, it treats conditions like anemia, osteoporosis, and muscle wasting due to severe illnesses. The undecanoate ester attached at the 17β position prolongs the drug’s half-life, reducing injection frequency by slowing the release of active nandrolone. Structurally, it crystallizes in a monoclinic space group, with strong intermolecular interactions, including bifurcated hydrogen bonds, contributing to its stability. The steroid backbone features a unique configuration of A, B, C, and D rings that enhance its physical properties. Soluble in lipid carriers, nandrolone undecanoate is formulated for injectable use, providing efficient delivery. While clinically beneficial, its misuse in sports for performance enhancement raises ethical concerns, emphasizing the need for regulated applications.

References:

Mare, L., Muresan-Pop, M., Purcea Lopes, P. M., Turza, A., Borodi, G., & Popescu, V., 2023. Crystal Structure and Intermolecular Energy for Some Nandrolone Esters. Molecules.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For more details consult with your doctor or healthcare professional.

FAQ
What is nandrolone undecanoate, and how does it work?
Nandrolone undecanoate is a long-acting esterified form of the anabolic steroid nandrolone. It binds to androgen receptors to promote muscle growth, enhance protein synthesis, and support recovery. The undecanoate ester prolongs its activity, reducing the frequency of injections needed.
References:

Mare, L., Muresan-Pop, M., Purcea Lopes, P. M., Turza, A., Borodi, G., & Popescu, V., 2023. Crystal Structure and Intermolecular Energy for Some Nandrolone Esters. Molecules.

What are the medical uses of nandrolone undecanoate?
This compound is used to treat conditions such as anemia, osteoporosis, and muscle wasting caused by severe illnesses like cancer or AIDS. Its ability to enhance muscle recovery makes it effective for these medical applications.
References:

Mare, L., Muresan-Pop, M., Purcea Lopes, P. M., Turza, A., Borodi, G., & Popescu, V., 2023. Crystal Structure and Intermolecular Energy for Some Nandrolone Esters. Molecules.

How is nandrolone undecanoate formulated for delivery?
Due to its poor water solubility, nandrolone undecanoate is dissolved in lipid-based carriers for injectable formulations. This ensures efficient delivery and prolonged release into the bloodstream.
References:

Mare, L., Muresan-Pop, M., Purcea Lopes, P. M., Turza, A., Borodi, G., & Popescu, V., 2023. Crystal Structure and Intermolecular Energy for Some Nandrolone Esters. Molecules.