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Cagrilintide acetate

Cagrilintide acetate

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Cagrilintide Acetate
Dragon Pharma
Substance Overview and History

Cagrilintide (AM833) is a modified amylin analog, developed for obesity management. By binding to both the amylin and calcitonin receptors, results in decreased food intake and significant weight reduction. Its mechanism Improves its effectiveness compared to traditional amylin treatments. In clinical trials, cagrilintide, alone or with semaglutide, has demonstrated notable weight loss benefits and It also offers promise for treating type 2 diabetes by improving blood glucose control and HbA1c levels.

References:

Larsen, A.T., Mohamed, K.E., Sonne, N., Bredtoft, E., Andersen, F., Karsdal, M.A. and Henriksen, K. (2022). Does receptor balance matter? – Comparing the efficacies of the dual amylin and calcitonin receptor agonists cagrilintide and KBP-336 on metabolic parameters in preclinical models. Biomedicine & Pharmacotherapy. Elsevier.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For more details consult with your doctor or healthcare professional.

FAQ
What is Cagrilintide?
Cagrilintide is a long acting amylin analog developed for the treatment of obesity.
References:

Larsen, A.T., Mohamed, K.E., Sonne, N., Bredtoft, E., Andersen, F., Karsdal, M.A. and Henriksen, K. (2022). Does receptor balance matter? – Comparing the efficacies of the dual amylin and calcitonin receptor agonists cagrilintide and KBP-336 on metabolic parameters in preclinical models. Biomedicine & Pharmacotherapy. Elsevier.

How exactly does Cagrilintide (AM833) mechanism of action function?
By stimulating both amylin and calcitonin receptors simultaneously it helps decrease appetite and encourages weight loss.
References:

Larsen, A.T., Mohamed, K.E., Sonne, N., Bredtoft, E., Andersen, F., Karsdal, M.A. and Henriksen, K. (2022). Does receptor balance matter? – Comparing the efficacies of the dual amylin and calcitonin receptor agonists cagrilintide and KBP-336 on metabolic parameters in preclinical models. Biomedicine & Pharmacotherapy. Elsevier.

What are the purposes for which Cagrilintide is utilized?
The main focus of Cagrilintides (AM833) development is to address obesity concerns.
References:

Larsen, A.T., Mohamed, K.E., Sonne, N., Bredtoft, E., Andersen, F., Karsdal, M.A. and Henriksen, K. (2022). Does receptor balance matter? – Comparing the efficacies of the dual amylin and calcitonin receptor agonists cagrilintide and KBP-336 on metabolic parameters in preclinical models. Biomedicine & Pharmacotherapy. Elsevier.