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Betamethasone Valerate

Betamethasone Valerate

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Substance Overview and History

Betamethasone valerate is a synthetic glucocorticoid designed to treat inflammation and autoimmune conditions, primarily in dermatology. As the 17-valerate ester of betamethasone, it offers enhanced topical action with reduced systemic effects. By modulating gene expression, it increases anti-inflammatory protein synthesis while suppressing inflammatory mediators, effectively reducing chronic inflammation. Introduced in 1967, it is approved for managing conditions like eczema and psoriasis.

References:

National Center for Biotechnology Information. "PubChem Compound Summary for CID 16533, Betamethasone Valerate" PubChem

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FAQ
What is Betamethasone Valerate?
Betamethasone Valerate is a synthetic glucocorticoid used to reduce inflammation and treat autoimmune skin conditions.
References:

National Center for Biotechnology Information. "PubChem Compound Summary for CID 16533, Betamethasone Valerate" PubChem

How does Betamethasone Valerate work?
It binds to intracellular glucocorticoid receptors, modifying gene expression to increase anti-inflammatory proteins and decrease inflammatory mediators.
References:

National Center for Biotechnology Information. "PubChem Compound Summary for CID 16533, Betamethasone Valerate" PubChem

What conditions is Betamethasone Valerate used for?
It treats skin conditions like eczema, psoriasis, and dermatitis, reducing redness, swelling, and itching.
References:

National Center for Biotechnology Information. "PubChem Compound Summary for CID 16533, Betamethasone Valerate" PubChem