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Sildanefil 100
Sildanefil 100 - ZPHC

Sildanefil 100 - ZPHC

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Category:
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Dosage:
100 mg/tab
Package:
10 tablets
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0
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Product Overview

Discovered by Pfizer researchers in the late 1980s, Sildenafil citrate (Viagra) emerged as a groundbreaking treatment for erectile dysfunction. Originally intended to address angina, scientists identified its potent effect on smooth muscle relaxation and blood flow. Viagra works by selectively inhibiting PDE5 and preserving cGMP levels within smooth muscle cells, facilitating vasodilation. Approved in 1998, Viagra swiftly became the premier ED treatment due to its favorable safety profile and high success rates, with dosing flexibility to meet individual patient needs. It remains widely prescribed for its effective action and well-established therapeutic profile.

References:

Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.

Disclaimer: Information provided it this page is for general information only and does not substitute for professional medical advice.

For detailed information about Sildanefil 100 by ZPHC, consult with your doctor or healthcare professional.

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FAQ
What was the original research goal behind Sildenafil citrate?
Researchers initially aimed to develop a selective inhibitor of PDE5 for treating cardiovascular diseases, particularly angina.
References:

Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.

What is the significance of phosphodiesterase type 5 (PDE5) in Sildenafil’s action?
PDE5 is an enzyme that breaks down cGMP; inhibiting it allows cGMP to accumulate, relaxing smooth muscle and improving blood flow.
References:

Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.

What medical issue was Sildenafil initially researched to treat?
Sildenafil was initially researched to treat angina, a cardiovascular condition.
References:

Dunzendorfer, U. (2012) Sildenafil. Switzerland: Birkhäuser Basel.